Insulin resistance and cancer

In the 8th Annual World Congress on Insulin Resistence, Diabetes and Cardiovascular which took place in Los Angeles, discussed the relation of insulin resistance and cancer. Herdie in his studies of researchers a motivator for AMPK and cancer describes breast cancer and colorectal cancer is especially associated with obesity and insulin resistance. AMPK activation leads to cell cycle of cancer cells at a standstill while the AMPK role to stop the activity of rapamycin (mTOR) which is activated within the tumors.

On breast cancer, the activation of AMPK is reduced which may be a mechanism for the development of cancer so in awarding research provides a benefit that patient metformin diabetes who get cancer incidents and metformin decreases metformin slowed the development of cancer in some animal models. Metformin will activate AMPK hepatic, lowering blood glucose levels, insulin and IGF1 so obtained anticancer effect.

Researcher Lorraine Lipscombe (Toronto, Canada) is also reviewing the existence of a link between cancer and diabetes and insulin resistance, some large clinics test data to see the relationship between cancer and type 2 diabetes, the initial report is from pancreatic cancer increased in patients who have been exposed to the old hepatoselular cancer diabetes, also associated with diabetes in patients without hepatitis C was found with the risk and non-alcoholic steatohepatitis cirrosis. Endometrial cancer has long been known as related to obesity is similar to the increased production of estrogens from adipose, but the influence of diabetes without obesity related also obtained on colorectal cancer.

In a review of clinical trials on patients with diabetic woman 75,000 control group showed cases of breast cancer is 2,85 vs. 2.64 per 1000/year, there was an increase of 8% to control obesity and other risk factors. Thus diabetes or any matters related to the diabetes appears to contribute to increased risk of breast cancer. In a meta-analysis of diabetes is also found in association with diabetes, the pancreas carcinoma liver and kidney, endometrium and although not as strong as the above, as well as cancer diabetes associated with colorectal cancer, and bladder cancer and little also looks at the rise in cases of cancer lymphoma.

The manarik is the Genesis cancer prostate decreased in patients of diabetes, researcher’s suspect possible relation between Lipscombe high occurrences of hipogonadisme. Potential mechanisms of diabetes trigger, the ferocity of the existence of the relationship between Hyperglycemia or the existence of indirect relationship between insulin resistance, inflammation, lipids and fatty acids that are abnormal, adipokine or IGF-1.

Another researcher, Warburg gave the dominant hypothesis of cancer cells use Glycolysis to gain energy and require high glucose conditions so that hyperglycemia gives a good environment for the development of cancer. Data intensive glucose control in relation to cancer and mortality of patients with cancer is still unclear, but the data showed a higher kegenasan happens by 30% in patients who get in the sulfonylurea and 90% compared to the patients of diabetes with insulin group who get metformin.

Researcher Pamela Goodwin (Toronto, Canada) further discusses the relationship between violence and the influence of insulin, metformin. A high BMI levels have a high risk of rekurensi cancer and increased mortality at local breast cancer with mediator poten i.e. inflammatory, adipokine, insulin, IGF and estrogen that may be related to one another. Cancer seen experiencing high expression of insulin levels, IGF-1, and hybrid receptors related to bad therapy results.

The alpha Isoform terekspresi on breast cancer is fatal receptors that would bind with IGF1 and IGF2 and menswitch will help metabolic process of insulin became influential lawsuit against mitogenik and anabolic steroid.

Advantages of the use of metformin is quite effective against several different subtypes of breast cancer but the difference that looks most effective is the triple negative breast cancer by pressing therapy resistance in human epidermal growth factor-2, increasing the effects of aromatase inhibitors and metformin in the animals try to look down the karsionogenesis lung induced by tobacco and provide benefit in the prevention of colon cancer.

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Healthy Diet Tips with Yogurt

Yogurt is safely consumed daily, and can help your diet program. The trick is to consume it twice a day, as the main menu and snack in between meals. Eat yogurt at breakfast or dinner, with by measure 200 milligrams per meal. Then eat one more time as a snack every day, with the same by measure.

This means that in one day, we recommend the consumption of 400 milligrams of yogurt. Free to choose of its kind. Can be frozen yogurt or yogurt liquid. Any flavors and varieties of yogurt, is safely edible for your diet menu, twice a day.

Yogurt is good for those who are living on a diet. Notably, since yogurt make healthy digestion. For diet programs, it is advisable to consume yogurt at breakfast. However, this option should be tempered by those who do not suffer from acute ulcer. People with acute ulcer are recommended against eating yogurt for breakfast, but replace the meals of yogurt in the evening and as a snack.

More details, the following menu diet with yogurt:

Breakfast

Breakfast with 200 milligrams of yogurt plus fresh fruit toppings. If you suffer from acute ulcer, replace yogurt with milk, bread or fruit for breakfast.

Lunch

Lunch as usual, with the content of carbohydrates, fiber, protein. However limit eating rice up to three to five spoons. While undergoing diet, carbohydrate intake remains unfulfilled ensure every day.

Dinner

Dinner with a vegetable and fruit. For acute ulcer sufferers, it is safe to eat dinner with the yogurt as well as to meet the intake of 200 milligrams of yogurt per meal.

Snack

The snack is important in between meals. I.e., at the time in between breakfast and lunch, also in between lunch and dinner. Well, the yogurt could be the choice of nibbles one among two options this snack time. By measure 200 milligrams per meal. That way, the needs of yogurt 400 milligrams per day are met, and can support your diet program.

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Legionnaires' Disease

Legionnaires' disease is a serious type of pneumonia — lung inflammation generally brought on by an infection. Legionnaires' illness is actually the result of a bacteria referred to as legionella, which are widespread in our environment. You can't catch Legionnaires' disease from person-to-person contact. Most people get Legionnaires' disease from inhaling the bacteria. You cannot catch it from another person or by drinking contaminated water. You usually get it by breathing in mist from water that contains the bacteria. They are found in natural water bodies such as rivers, lakes, creeks and hot springs. The bacteria are also found in spas, potting mix, warm water systems and artificial systems that use water for cooling, heating or even commercial procedures, for example air conditioning systems.

Symptoms of Legionnaires' disease include fever, chills, a cough and sometimes muscle aches and headaches. Other forms associated with pneumonia possess comparable signs and symptoms. You will probably need a chest x-ray to identify the pneumonia. Lab tests may identify the specific bacteria which trigger Legionnaires' disease.

Legionella bacteria additionally lead to Pontiac fever, the less severe illness resembling the flu. Separately or together, the two illnesses are sometimes called legionellosis. Pontiac fever usually clears on its own. But Legionnaires' disease is actually severe and may end up being life-threatening. Untreated Legionnaires' disease can be fatal. Although prompt treatment with antibiotics usually cures Legionnaires' disease, some people continue to experience problems after treatment.

Some people are at greater risk of infection compared to other people
Although this is a common bacterium in the environment, only a few people who come in contact with the bacteria become infected. Some people are at greater risk, such as:

• People over 50 years of age
• Smokers
• People with chronic illness
• People with medical conditions that impair their immune system.

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Heart Attack Signs

Heart and blood vessels diseases have long been recognized among the biggest cause of death in the world. Even on the basis of the data, 40 million people globally die each year from this disease.

What concerns, heart disease can result in unexpected death. This needs to be wary because of heart disease can strike anyone indiscriminately.

There are typical signs and symptoms of heart disease which is worth a look out for. Often experiencing tightness in your chest is is one of the typical symptoms of heart disease. If you are experiencing these symptoms, check to see a doctor immediately. So, if you do not immediately get medical help, lives can be bet.

To that end, in order to be aware of heart attack, you need to know the typical symptoms that can appear suddenly:

1. Sudden pain in the chest behind the sternum or like chest tightness.
2. Repeated Chest pain in a few minutes (20 minutes or more).
3. Pain in the form of pressure in the chest, and neck seems to choke up to lead out cold sweat
4. Suddenly fainted, but could be regained conscious. This happens because there is a heart rhythm disorder

In addition to the typical symptoms of the above, there are some hidden symptoms of heart disease, that feel like gastritis, whereas before never suffer gastric disorders. Is typically sudden symptoms of gastritis appeared in the early days to arise in at 10 am. This occurs because of increased sympathetic dystrophy nervous in the morning.

If you are experiencing these symptoms, try settles down and drink aspirin as a temporary shock medicine. Next, immediately contact your doctor in order to get help immediately.

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Detect Cancer Symptoms Early

To prevent cancer is better than to cure one. However, the awareness of people against cancer as well as prevention strategies is still very low. Whereas, detecting cancer early may help treatment in order to more effectively.

How women can reduce the risk of cancer? Papanikolaou test or pap smear, Mammography or breast examinations using low-dose x-ray is extremely important to detect cervical cancer or breast cancer. However these tests are not enough to protect yourself from all types of cancer.

Contact with the radiation, smoke, alcoholic beverages, as well as chronic bacterial infections tend to be a few of the elements recognized to increase risk associated with most cancers. Whilst additional elements might impact the risk from the illness is actually diet plan as well as obesity.

For that, The Times of India renders on their site, the information from Dr. Ashok Vaid, head of the Oncology Institute of the health of Artemis in Gurgaon, Haryana, India, regarding a few of the signs and symptoms associated with most cancers observed in women. If you think the women frequently experience the following indicators, means it is time to visit a doctor.

1. Drastic weight loss due to unexplainable reasons, lost appetite, or easily tired.
   
2. A mouth wound that never heal.
   
3. Hard to swallow.
   
4. Abnormal Swelling at the neck, down the arm, or in any part of the body.
   
5. Breast swelling, abnormal fluid coming out of the nipple.
   
6. Coughing quite a long time, sometimes even with blood.
   
7. Flatulence or bleeding in the rectum.
   
8. Excessive bleeding when menstruation.
   
9. Abnormal fluid that comes out through the vagina or bleeding after sex.
   
10. Urine or waste that comes with blood.
    

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Identify Early Ovarian Cancer Symptoms

Researchers from the United Kingdom found seven symptoms related to ovarian cancer. This discovery break the statement that ovarian cancer is a cancer that silent killer. Said to be the silent killer because it usually occurs without symptoms prior to an advanced stage.

"Ovarian cancer is not silent, it's noisy. It's just we're not very good at deciphering the noise." said study leader William Hamilton, MD, from the University of Bristol, was quoted as saying the site WebMD. 4% of women suffered cancer, according to Hamilton, is this cancer. But this ovarian cancer has a prognosis/prospect of the worst of all kinds of gynecological cancer.

Research

In a study published on BMJ.com, researchers evaluate 212 women aged 40 or over. These women have been diagnosed suffering from early stadium ovarian cancer. The researchers then compare them with healthy women 1,060.

The researchers checked participant’s medical records, 1 year before being diagnosed with cancer. The same is also done against healthy women. The researchers noted the symptoms experienced by the participants and times when they feel it.

The results of studies

The study found 7 symptoms related to cancer of the ovaries. These symptoms include:

1. Abdominal distension
2. Increased frequency of urinary
3. Post-menopausal Bleeding
4. Abdominal pain
5. Lost appetite
6. Bleeding through the rectum
7. A bloated stomach

Of the seven symptoms, abdominal distension is most symptoms associated with ovarian cancer. Hamilton gives a value of 2.5%. "2.5% means, 1 in 40 women who experience these symptoms will suffer ovarian cancer.” These figures, according to Hamilton, are quite high and comparable to the risk of lung cancer when you cough up blood or the risk of colon cancer when you are bleeding from the rectum.

While researching further, they found the participants already have 3 ovarian cancer symptoms include abdominal pain, abdominal distension, and increased frequency of urinary, at least 6 months before being diagnosed. And these symptoms were significantly related to ovarian cancer.

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